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So, worrying a bone like a dog, I just can't leave the Journal of Alzheimer's alone.

I succumbed to the enticingly named: "Alzheimer’s Disease: Key Insights from Two Decades of Clinical Trial Failures"
https://content.iospress.com/articles/journal-of-alzheimers-disease/jad215699

and seriously, one of the major conclusions is: maybe if we just try harder.

Okay, the language is thus: "Our evaluation found that rational drug development principles were not always followed for AD therapeutics development, and the question remains whether some of the failed compounds may have shown efficacy if the principles were better adhered to."

It couldn't possibly be because this tree has no alzheimers, nope. Gonna bark at that tree forEVEEEEEEER.

more *sigh*

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agoodwinsmith

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