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Coffee and Alzheimer's, some more
Jul. 26th, 2023 02:41 pmSo this new study:
Espresso Coffee Mitigates the Aggregation and Condensation of Alzheimer′s Associated Tau Protein
out of University of Verona in Italy
as published in the Journal of Agriculture and Food Chemistry
https://pubs.acs.org/doi/10.1021/acs.jafc.3c01072
says that Espresso coffee (and beverages made of same) and its components (caffeine, genistein, chlorogenic acid) interferes with the formation & toxicity of tau proteins.
" ... we have presented a large body of evidence that espresso coffee, a widely consumed beverage, is a source of natural compounds showing beneficial properties in ameliorating tau-related pathologies."
I am not going to pretend that was an easy read prior to the Discussion section. I will say that I am always skeptical of studies that isolate each component so rigorously because none of my components are isolated. I'm more interested in synergies. For instance: what happens to caffeine and chlorogenic acid when they hit the hydrochloric acid in my tummy while I eat a nice sugary rice crispy square?
Anyhoo - looking up genistein and chlorogenic acid is worth your time, too.
Oh yeah, funky factoid of the day: if you eat your coffee perked or espressoed, then you will get the cholesterol lurking in it, which may or may not worsen your cholesterol counts, depending on your genetics. However, if you have it dripped through a paper filter, you will not.[1]
[1] - I have been trying to improve my cholesterol counts through diet, and it is things like this that drive me directly to the bacon and cheese (grilled, *with* french fries) sandwich, Pfff.
Espresso Coffee Mitigates the Aggregation and Condensation of Alzheimer′s Associated Tau Protein
out of University of Verona in Italy
as published in the Journal of Agriculture and Food Chemistry
https://pubs.acs.org/doi/10.1021/acs.jafc.3c01072
says that Espresso coffee (and beverages made of same) and its components (caffeine, genistein, chlorogenic acid) interferes with the formation & toxicity of tau proteins.
" ... we have presented a large body of evidence that espresso coffee, a widely consumed beverage, is a source of natural compounds showing beneficial properties in ameliorating tau-related pathologies."
I am not going to pretend that was an easy read prior to the Discussion section. I will say that I am always skeptical of studies that isolate each component so rigorously because none of my components are isolated. I'm more interested in synergies. For instance: what happens to caffeine and chlorogenic acid when they hit the hydrochloric acid in my tummy while I eat a nice sugary rice crispy square?
Anyhoo - looking up genistein and chlorogenic acid is worth your time, too.
Oh yeah, funky factoid of the day: if you eat your coffee perked or espressoed, then you will get the cholesterol lurking in it, which may or may not worsen your cholesterol counts, depending on your genetics. However, if you have it dripped through a paper filter, you will not.[1]
[1] - I have been trying to improve my cholesterol counts through diet, and it is things like this that drive me directly to the bacon and cheese (grilled, *with* french fries) sandwich, Pfff.
